Tuesday, February 26, 2013

Bacteria

FAR121/4 Microbiology for Pharmacy
Lecture bacteriuml Genetics (4 hours) by Dr. Suriani Mohamad

References
cellular telephone and Molecular Biology Molecular Biology of The Cell Principals of Genetics

What Is Genetics
? field of honor of heredity or transmission of information from an organism (pargonnt) to its upshot (offspring/children)

? Genetic information is stored in the form of DNA (however, in certain viruses, genetic material is stored in the form of RNA, eg. severe acute respiratory syndrome virus, HIV)

THE BACTERIAL GENOME
GENOME: the complete collection of hereditary information for an individualist organism. Hereditary information exists in the form of DNA (deoxyribonucleic acid) Bacteria genome: chromosome + extra chromosomal DNA molecules ( plasmid DNAs, episomes) Single chromosome: Escherichia coli, Klebsiella sp., Mycobacterium sp. etcetera Two chromosomes: Burkholderia sp., Ralstonia sp., Vibrio cholerae.

Extra Chromosomal DNA
Plasmids: circular repeat stranded DNA molecule that replicates independently (autonomous replication). May take over one or more (non-essential) genes, smaller than the bacterial chromosome. normally expresses genes that allows the bacterium to adapt to a certain situation.

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Most plasmids are classified by some recognizable functions that they serve in a bacterium, among them: a) F plasmid (fertility factors), b) R plasmids (Resistance) c) Virulence plasmids d) Bacteriocins e) Ti (Tumor-inducing) plasmids slew cause tumor in plants.

F plasmid (fertility factors), Carries rep and tra genes Transmissible or non transmissible plasmids R plasmids (Resistance) fill genes that provides apology to various antibiotics (eg. catR, tetR, kanR) generally contains two components: a safeguard transfer factor (RTF) & one or more resistance (R) genes. RTF mediates transfer of genetic material via conjugation & therefore can transfer resistance to another organism emergence of bacterial populations that are highly resistant to...If you want to get a full essay, order it on our website: Orderessay



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